| 2015年
12月31日 | 2016年
12月31日 | 2017年
12月31日 | 2018年
12月31日 | 2019年
12月31日 | 2020年
12月31日 | 2022年
12月31日 |
|---|
| Net loss | -17,352,073 | -19,166,753 | -15,419,308 | -13,368,098 | -12,446,458 | -26,210,844 | -37,283,233 |
|---|
| Depreciation and amortization | 624,653 | 656,047 | 669,088 | 730,884 | 921,379 | 2 | 2 |
|---|
| Noncash interest expense | - | 4,527 | 185,294 | 133,802 | 13,158 | 3 | 2 |
|---|
| Change in inventory reserve | - | - | - | - | - | - | 2 |
|---|
| Stock compensation expense | 1 | 945,461 | 911,398 | 862,281 | 372,870 | 316,086 | 950,935 |
|---|
| Loss on sale of equipment | - | 6,309 | - | 5,253 | -9,904 | 100,000 | -16,000 |
|---|
| Gain on extinguishment of debt | - | - | - | - | - | 884,970 | - |
|---|
| Change in fair value of derivative financial instruments | - | - | -144,064 | -8,386 | -67 | -517,680 | -113,740 |
|---|
| Impairment of right-of-use asset | - | - | - | - | 520,759 | 101,838 | - |
|---|
| Impairment of intangible assets | - | - | - | - | - | 750,596 | 5 |
|---|
| Goodwill impairment charge | - | - | - | - | - | - | 7 |
|---|
| Accounts receivable | -359,298 | 136,226 | 260,471 | -432,814 | 195,019 | -438,284 | -587,761 |
|---|
| Inventory | -424,505 | 20,179 | -161,027 | 11,273 | -70,286 | 410,341 | 728,548 |
|---|
| Other assets | 319,305 | 263,882 | 315,688 | -486 | -577,193 | -1,152,200 | -151,456 |
|---|
| Accounts payable | 196,444 | -53,229 | -563,357 | 89,493 | -503,516 | -481,453 | -814,299 |
|---|
| Accrued compensation and other liabilities | -1,508,937 | -163,223 | 399,224 | 77,871 | -818,433 | -1,559,881 | -1,287,874 |
|---|
| Deferred revenue | -288,246 | -13,528 | -12,955 | - | - | - | 139,570 |
|---|
| Net cash used in operating activities | - | - | - | -11,073,997 | -11,505,439 | -23,396,532 | -20,449,698 |
|---|
| Purchases of property and equipment | 185,296 | 123,514 | 276,950 | 147,767 | 31,826 | 130,354 | 590,772 |
|---|
| Net cash used in investing activities | - | - | - | -137,327 | -2,502,576 | -1,063,505 | -590,772 |
|---|
| Proceeds from at the market offering, net of issuance costs | 17 | 4 | 4 | 597,743 | 5 | 16 | 989,704 |
|---|
| Proceeds from issuance of common stock and pre-funded warrants in registered direct offering, net of issuance costs | - | - | - | - | - | - | 3 |
|---|
| Proceeds from the exercise of common warrants | - | - | - | - | - | 2 | - |
|---|
| Payments on debt | 155,000 | 178,997 | 1 | 371,573 | 828,850 | 998,182 | 11 |
|---|
| Payments on finance lease obligations | - | - | - | - | 535,931 | 579,029 | 43,150 |
|---|
| Net cash (used in) provided by financing activities | - | - | - | 14 | 12 | 34 | -6,735,681 |
|---|
| Effects of exchange rates on cash | - | - | - | 12,878 | -3,735 | 2 | -920,376 |
|---|
| Net (decrease) increase in cash, cash equivalents and restricted cash | - | - | - | 3 | -1,843,604 | 11 | -28,696,527 |
|---|
| Cash paid for interest | - | - | - | 57,393 | 187,359 | 952,050 | 1 |
|---|
| Right-of-use assets acquired through operating leases | - | - | - | - | - | 1 | - |
|---|
| Property and equipment transferred to inventory | - | - | - | - | - | - | 152,243 |
|---|