| 2015年 12月31日 | 2016年 12月31日 | 2017年 12月31日 | 2018年 12月31日 | 2019年 12月31日 | 2020年 12月31日 | 2021年 12月31日 | 2022年 12月31日 |
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Net loss | - | - | - | -96 | -66 | -92 | -350 | -417 |
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Stock-based compensation expense | 211 | 74 | 37 | 23 | 3 | 2 | 57 | 40 |
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Fair Value Adjustment of Warrants | 1 | - | - | - | - | - | - | -13 |
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Transaction Costs, Warrant Liability | - | - | - | - | - | - | - | 1 |
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Depreciation and amortization | 1 | 4 | 6 | 10 | 9 | 9 | 14 | 18 |
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Non-cash interest items, net (including amounts with related parties) | - | - | - | - | - | 0 | -12 | -12 |
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Amortization of related-party notes discounts | - | - | - | - | - | - | - | 16 |
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Operating Lease, Right-of-Use Asset, Amortization Expense | - | - | - | - | - | - | - | 6 |
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Amortization of premiums, net of discounts, on marketable debt securities | 0 | -2 | -2 | -0 | - | -1 | - | -1 |
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Unrealized losses (gains) on equity securities | - | - | - | - | - | - | -5 | -4 |
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Unrealized loss on non-marketable equity investment | - | - | - | - | - | 1 | - | - |
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Impairment of intangible assets | - | - | - | - | - | - | - | 1 |
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Impairment of fixed assets | - | - | - | - | - | - | - | 1 |
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Deferred tax | -0 | -1 | -0 | -0 | - | - | -0 | -0 |
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Other | - | - | - | - | - | - | 0 | 0 |
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Prepaid expenses and other current assets | 3 | - | -0 | 10 | -9 | 1 | 2 | 17 |
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Investment and other assets | 1 | -0 | -0 | 1 | 4 | 0 | 4 | -2 |
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Accounts payable | - | - | - | - | - | - | -4 | 8 |
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Accrued expenses and other liabilities | 2 | 2 | -0 | 13 | -12 | 4 | 5 | 4 |
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Related parties | - | - | - | - | - | - | -10 | -1 |
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Operating lease liabilities | - | - | - | - | - | -4 | -4 | -4 |
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Net cash used in operating activities | - | - | - | -63 | -61 | -70 | -274 | -337 |
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Purchases of property, plant and equipment | 2 | 7 | 35 | 13 | 4 | 3 | 34 | 78 |
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Purchase of intangible assets | - | - | - | - | - | - | - | 21 |
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Proceeds from sales of property, plant and equipment | - | - | - | 0 | - | - | 20 | - |
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Purchases of marketable debt securities, available-for-sale | 198 | 273 | 111 | - | - | - | 142 | 34 |
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Maturities of marketable debt securities, available for sale | - | - | - | - | - | 65 | 56 | 128 |
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Proceeds from Sale and Maturity of Marketable Securities | 27 | 166 | 254 | 165 | 112 | - | 14 | 34 |
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Investment in joint venture – an equity method investment | - | - | - | - | - | - | - | 1 |
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Net cash provided by (used in) investing activities | - | - | - | 57 | 21 | -21 | -85 | 27 |
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Proceeds from Related Party Debt | - | - | - | - | - | - | 339 | 174 |
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Proceeds from Issuance of Common Stock | - | - | - | - | - | 86 | 165 | 60 |
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Proceeds from Stock Options Exercised | 1 | 1 | 1 | - | - | 1 | 5 | 0 |
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Proceeds from Contributions from Affiliates | - | - | - | - | - | - | 1 | - |
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Net share settlement for RSUs vesting | 2 | 1 | 1 | 0 | 0 | 1 | 4 | 1 |
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Principal payments of finance leases | - | - | - | - | - | - | - | 0 |
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Payment for contingent consideration | - | - | - | - | - | - | 0 | 0 |
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Net cash provided by financing activities | - | - | - | -1 | 39 | 87 | 505 | 234 |
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Effect of exchange rate changes on cash, cash equivalents, and restricted cash | - | - | - | - | - | - | 0 | 0 |
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Net change in cash, cash equivalents, and restricted cash | - | - | - | - | - | - | 146 | -76 |
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Interest | - | 0 | 1 | 0 | 0 | 0 | 2 | 35 |
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Income taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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Gain on extinguishment of debt with related parties under common control | - | - | - | - | - | - | - | 83 |
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Debt Conversion, Converted Instrument, Amount | - | - | - | - | 1 | - | - | 52 |
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Issuance Of Warrants | - | - | - | - | - | - | - | 35 |
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Right-of-Use Asset Obtained in Exchange for Operating Lease Liability | - | - | - | - | - | 5 | 23 | 15 |
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Capital Expenditures Incurred but Not yet Paid | - | - | - | - | 0 | 0 | 12 | 13 |
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Stock Issued | - | - | - | - | 0 | 1 | 1 | 11 |
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Right-of-Use Asset Obtained in Exchange for Finance Lease Liability | - | - | - | - | - | - | - | 0 |
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Unrealized Gain (Loss) on Investments | 0 | -0 | -0 | 0 | 0 | -0 | -0 | -0 |
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Accrued investment in joint venture | - | - | - | - | - | - | 1 | - |
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